Never. Turns out my issue was undiagnosed ADHD and trauma. Therapy and adderall have done wonders for me. I was trying to treat depression by itself, not as a side effect of another issue.
Similar case for me, but I would recommend OP or anyone reading to work it through with their doctor (or even switch), being honest with them and oneself.
Yes exactly. It took me a few doctors to figure out what was going on because the first couple didn’t ask the questions that the doctor who diagnosed me did.
Me too, only add autism
I’m not officially diagnosed autism but my doctor said I meet the criteria but didn’t want it written down due to the political climate.
Define ‘working’ becsuse a lot of strife can come from the differences between what you’re expecting it to do and what will actually happen. For me, it just made it easier for me to lift myself out of bed in the morning and that’s about where the progress ends. And that’s the one I found after years of trying ones that were worse. They’re not happy pills, they just let you deal with the horrible shit instead of becoming immobilized by it.
I took estrogen for depression, it started working within a week :p
Sounds like I should test if going on testosterone does the same someday.
wtf same?? 😮
solution: everyone gets free estrogen! /j
@meow@discuss.tchncs.de
I may need to confirm this theory
Escitalopram took only one day for me. For both anxiety and depression.
Bupropion took 3-4 weeks. For depression.
Trintellix took about 2 weeks. For anxiety.
I didn’t even realize my anxiety was bad until I started getting heart palpitations. I now take escitalopram and it stopped within like a week.
Escitalopram fixed my Raynaud’s at a low “taper up” dose basically immediately. Although it wasn’t prescribed for that, this was just a happy side effect. I guess some SSRIs do that.
For depression, it took about a month to ramp up enough to see a difference. It did ease the anhedonia, but it also masked my emotional flashbacks until it was too late to disrupt them.
I also had SEVERE issues with my sodium while on it, which is why I didn’t stay on it past a month. However, I don’t snack or eat salty stuff so someone with higher sodium intake might have fared better.
I would have tried to get used to it to see if the masking of the early signs of flashbacks got better as I got used to it if it hadn’t messed up my sodium so badly.
Also, the sexual side effects are real.
Escitalopram also worked quick for me, but killed my libido
It was my miracle cure until I switched to Trintellix. Yes, it killed my libido as well, but Trintellix is not as bad.
I’ll talk to my Dr. Thanks!
I, too, would like to talk to your Dr. Thanks.
Dr thanks is the most greatful person I’ve encountered
I started Escitalopram 4 weeks ago. Not motivated for anything yet and my brain still feels like it’s filled with cotton, but I can at least sleep again and don’t panic about every small thing anymore.
About a month for me. I’m taking both. It needs to build up in the system if I understood what the doctor said right.
(Edit: and booze completely kills it, just saying)
They never worked. For some unlucky people, anti-depressants just straight up don’t work. If you’re new at it, keep at it, but if it’s been a few months it might be time to switch medication. if you’ve already switched a bunch of times, they might not work for you and your only option is probably therapy
“Some unlucky people” turns out to be 85% of people with depression. What that suggests to me is that depression is a syndrome with multiple causes, and typical antidepressant drugs treat one of them.
Seems to only mention SSRI specifically, not about antidepressants in general
Also this: “suggested that the active ingredients in 10 of the most popularly prescribed antidepressant medications made a meaningful difference in only 15 percent of the patients who took them, almost always in those patients suffering from the most severe depression”
So yeah… that’s me lmfao…
Hey OP, I’m glad you’re fighting this fight. You’re worth it and I’m glad to have you around.
There actually are other options for treatment-resistant depression, which is defined as depression that has little or no response to standard treatments like antidepressants.
- Transcranial magnetic stimulation (TMS): uses magnetic currents to stimulate the brain while awake, typically provided 5x per week for 6 weeks (although there are now newer protocols that are much shorter in duration)
- Ketamine: a general anesthetic drug typically provided via a nose spray 1-2 times per week for 8 weeks
- Electroconvulsive therapy (ECT): uses electricity to induce a small seizure in the brain under sedation, typically provided 2-3 times per week for 3-4 weeks
I try to spread the word about these treatments when I can because TMS helped me immensely after trying just about every antidepressant out there with no luck.
To fully work? About a year. To some improvement, 3 months.
Depression. Sertraline/Zoloft. Months.
Initially, it helped a small amount. Possibly placebo. It was well-tolerated, so the dose was doubled. Then months (maybe 3?) of slight improvement.
But when it really took hold it felt sudden.
Depends on the meds, and they can have a drastically different effect on people.
Duloxetin: days, full effect after about a month (side effects after a year or so)
Sertraline: never worked, in fact made stuff worse
Prefaxine: about three weeks to feel noticeable effect.I have now been on anti-depressants for almost five decades. In that time, I’ve used just about everything out there, and transitioned from one to the next. Unfortunately, the honest answer is that how long they take to kick in varies widely based on the specific medication. I’m sure the patient’s condition can also change it by quite bit. My average has been around a month to get a useful effect, but my minimum is probably around a week and my maximum more like three months.
Fluoxetin: ~7 Weeks, 12 full effect.
Seratrelin: pretty much instant (side effects) main effect like never idk
Zoloft, it took three days to start working. It had been an absolute gamechanger for my anxiety and I love it. 10/10
Anxiety meds typically a few days to start to notice. Depression meds either had severe negative side effects almost immediately, or positive effects would start showing up after 2 or 3 weeks.
I’ve taken a bunch of anxiety meds. The only one that worked somewhat was Ativan, but I stopped after a few weeks because I was too anxious about taking it regularly and developing a benzo addiction.
Never worked












